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UID:20251028T071423EDT-1148T3DuK9@132.216.98.100
DTSTAMP:20251028T111423Z
DESCRIPTION:Special Seminar\n	Selective Neuronal Vulnerability in Neurodegen
 erative Diseases\n\n\nSerge Przedborski\, MD\, PhD \n	Departments of Neurol
 ogy\, Pathology\, Cell Biology\, and Neuroscience\n	Columbia University\, N
 ew York\n\nIn person: de Grandpré Communications Centre \n\nOnline: ZOOM\n
 \nDr. Przedborski is an internationally recognized leader in the field of 
 neurodegenerative disorders\, with core research interests focused on the 
 molecular and cellular pathology of Parkinson’s Disease (PD) and Amyotroph
 ic Lateral Sclerosis (ALS). His laboratory systematically investigates the
  complex roles of both cell-autonomous and non-cell-autonomous mechanisms 
 in neurodegeneration\, focusing on differential neuronal susceptibility. T
 his is achieved using a combination of toxic and genetic models\, as well 
 as postmortem tissues from PD and ALS patients.\n\nKey ongoing research ar
 eas include:\n\n\n	Mitochondrial Biology: A primary focus is to understand 
 how mitochondrial dysfunction and altered communication with other organel
 les\, such as the endoplasmic reticulum\, contribute to cellular perturbat
 ions\, including lipid dyshomeostasis\, and ultimately lead to the degener
 ation of specific neuronal subpopulations.\n	Non-Neuronal Cell Contribution
 s: Another key line of inquiry explores the extent to which non-neuronal c
 ells\, such as astrocytes and microglia\, participate in the degeneration 
 of neighboring neurons.\n\n\n \n\nDr. Przedborski’s standing in the field 
 is evidenced by his significant editorial and review service to the global
  scientific community\; he holds editorial positions\, serving as an Assoc
 iate Editor for the NPJ Parkinson’s Disease and as a Reviewing Editor for 
 eLife. Furthermore\, his expertise is routinely sought by top-tier funding
  agencies and publications\, including his service as a reviewer for the N
 ational Institutes of Health (NIH)\, the Canadian Medical Research Council
 \, and high-impact journals such as Science\, Nature\, Nature Neuroscience
 \, Neuron\, the New England Journal of Medicine\, and the Proceedings of t
 he National Academy of Sciences USA.\n
DTSTART:20251029T163000Z
DTEND:20251029T173000Z
LOCATION:Hybrid: de Grandpré Communications Centre\, The Neuro and Zoom\, M
 ontreal Neurological Institute\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue U
 niversity
SUMMARY:Special Seminar: Selective Neuronal Vulnerability in Neurodegenerat
 ive Diseases
URL:/medhealthsci/channels/event/special-seminar-selec
 tive-neuronal-vulnerability-neurodegenerative-diseases-368451
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